HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2E)-3-(3-Nitrophenyl)acryloyl chloride → 2-[(E)-2-(3-amino-phenyl)-vinyl]-7,7-dimethyl-5-pentyl-5,7-dihydro-1H-imidazo[4,5-f]indol-6-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2E)-3-(3-Nitrophenyl)acryloyl chloride | HCID 11063737 | — |
| Reactant | 5-Amino-3,3-dimethyl-6-nitro-1-pentyl-1,3-dihydro-indol-2-one | HCID 17802744 | — |
| Product | 2-[(E)-2-(3-amino-phenyl)-vinyl]-7,7-dimethyl-5-pentyl-5,7-dihydro-1H-imidazo[4,5-f]indol-6-one | HCID 67426692 | 52.9% |
Reaction Steps
2-[(E)-2-(3-Amino-phenyl)-vinyl]-7,7-dimethyl-5-pentyl-5,7-dihydro-1H-imidazo[4,5-f]indol-6-one (177 mg) is prepared from A8 (251 mg) and (E)-3-(3-nitro-phenyl)-acryloyl chloride (200 mg; 1.01 mmol) as described in Example 28a and b.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07714010B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-7d87ab299c724f638f2e2cbe1eac1e32 |
| Source note | uspto-grants-2010_05 |