HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenepropanoyl chloride → N-(3,3-dimethyl-6-nitro-2-oxo-1-pentyl-2,3-dihydro-1H-indol-5-yl)-3-phenyl-propionamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenepropanoyl chloride | HCID 64801 | — |
| Reactant | 5-Amino-3,3-dimethyl-6-nitro-1-pentyl-1,3-dihydro-indol-2-one | HCID 17802744 | — |
| Product | N-(3,3-dimethyl-6-nitro-2-oxo-1-pentyl-2,3-dihydro-1H-indol-5-yl)-3-phenyl-propionamide | HCID 23092643 | 99.7% |
Reaction Steps
N-(3,3-Dimethyl-6-nitro-2-oxo-1-pentyl-2,3-dihydro-1H-indol-5-yl)-3-phenyl-propionamide (1.17 g) is synthesized from A8 (807 mg) and freshly prepared 3-phenyl-propionyl chloride (0.5 ml; 3,3 mmol) as described in Example 1a.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07714010B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-c59c236d61074a65b91e010b517653df |
| Source note | uspto-grants-2010_05 |