HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl chloride → HCID 178429303, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 178429304 | HCID 178429304 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178429303 | HCID 178429303 | — |
Reaction Steps
A solution of D8 (120 mg), benzoic acid chloride (87 μl), NEt3 (150 μl) in THF (1 ml) and CH2Cl2 (3 ml) is stirred at RT for 3 h. After evaporation EtOAc is added and the organic phase is washed with saturated NaHCO3 solution and brine, dried over MgSO4 and evaporated again. The residue is purified by preparative RP-HPLC to give the desired compound (13.4 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07714010B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-e886a695be5f4ad2b99ff11dc6469a1c |
| Source note | uspto-grants-2010_05 |