Acetic Acid → HCID 58896500, compound

Participants

Reaction Steps

To a solution of N2-mesityl-5-methyl-1,3-benzothiazole-2,7-diamine (10 mg, 0.0336) in dichloromethane (1 ml) was added propionaldehyde (0.012 ml, 0.168 mmol) followed after 30 min by sodium triacetoxyborohydride (29 mg, 0.135 mmol) and AcOH (0.0039 ml). The mixture was stirred at room temperature for 18 h. The reaction was quenched with saturated NaHCO3 solution. The aqueous solution was extracted with dichloromethane. The extract was washed with brine, dried over magnesium sulfate and concentrated under vacuum. The residue was triturated with n-hexane. The resulting solid was collected by filtration to afford 6.8 mg of the title compound.

Provenance & Evidence