HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[3-(tert-Butyldimethylsilyloxymethyl)phenyl]-3-mesitylthiourea → 1-(3-Hydroxymethylphenyl)-3-mesitylthiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[3-(tert-Butyldimethylsilyloxymethyl)phenyl]-3-mesitylthiourea | HCID 87505147 | — |
| Catalyst | Hydrochloric Acid | HCID 313 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1-(3-Hydroxymethylphenyl)-3-mesitylthiourea | HCID 86049116 | 86.3% |
Reaction Steps
To 0.56 g (0.1.4 mmol) of 1-[3-(tert-butyldimethylsilyloxymethyl)phenyl]-3-mesitylthiourea in 10 mL of ethanol was added 10 drops of concentrated hydrochloric acid. After 30 min, the reaction was diluted with water and the precipitate that formed was collected to give 0.35 g (86%) of the title compound as a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07714009B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-627e7054d6c94f209827bcfc7adffd8c |
| Source note | uspto-grants-2010_05 |