Methyl 4-tert-butyl-3-(prop-1-en-2-yl)benzoate → Methyl 4-tert-butyl-3-isopropylbenzoate

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Reaction Steps

To the ester 26.2 (167 mg, 0.72 mmol) in EtOH/EtOAc (1/1, v/v, 3.00 mL), was added Pd(OH)2/C (10 mg). The mixture was placed under an atmosphere of hydrogen and stirred for 8 days. The resulting mixture was filtered through Celite and concentrated in vacuo to give a clear oil (145 mg, 86%). The crude product (26.3) was used in the next step without further purification.

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