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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2235712Generated: November 1, 2026

Hydrochloric Acid → 5-Chloro-2-(3,4,5-trifluorophenyl)pentanoic acid hydrazide hydrochloride

https://huagongshe.com/reaction/2235712

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactanttert-butyl N'-[5-chloro-2-(3,4,5-trifluorophenyl)pentanoyl]hydrazinecarboxylateHCID 66839143—
SolventAcetic AcidHCID 176—
SolventEthyl AcetateHCID 8857—
Product5-Chloro-2-(3,4,5-trifluorophenyl)pentanoic acid hydrazide hydrochlorideHCID 66839231200.1%

Reaction Steps

A solution of 4 N hydrochloric acid in acetic acid (2 mL) was added to a solution of tert-butyl N′-[5-chloro-2-(3,4,5-trifluorophenyl)pentanoyl]hydrazinecarboxylate (300 mg) in ethyl acetate (2 mL), and the reaction solution was stirred at room temperature for one hour. The reaction solution was concentrated under reduced pressure to obtain 250 mg of the title compound. The property value of the compound is as follows.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07713993B2
Source datasetuspto-grants-2010_05
ORD IDord-dc0d85498dca445088af4b1b1b4b26ba
Source noteuspto-grants-2010_05