HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 223592Generated: October 30, 2026
HCID 178422887, compound → HCID 178422888, compound
https://huagongshe.com/reaction/223592
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 178422887 | HCID 178422887 | — |
| Solvent | Hexane | HCID 8058 | — |
| Solvent | 1,1'-Biphenyl, mixt. with 1,1'-oxybis(benzene) | HCID 24670 | — |
| Product | HCID 178422888 | HCID 178422888 | 66.5% |
Reaction Steps
A mixture of 2.4 g (0.009 mol) of 3-carboxy-4-hydroxy-7-methylpyrido[3',2':4,5]-thieno[3,2-C]pyridazine in 70 ml of Dowtherm-A was stirred at 225° C. for 30 minutes. It was cooled, diluted with hexane and filtered. The crude product was crystallized by 5% NaOH/HOAC giving 1.3 g (65%) of 4-hydroxy-7-methylpyrido[3',2':4,5]thieno[3,2-C]pyridazine, m.p.>300° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04355164 |
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| Source dataset | uspto-grants-1982_10 |
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| ORD ID | ord-db23a7df47ce43e88181e32cd36573c0 |
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| Source note | uspto-grants-1982_10 |
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