3,4-Dichloro-5-isothiazolecarboxylic acid → 3,4-Dichloro-5-isothiazolecarbonyl chloride

Participants

Reaction Conditions

Reaction Steps

To 4.0 g (20.3 mmol) of 3,4-dichloroisothiazole-5-carboxylic acid were added 8 ml of oxalyl chloride and a catalytic amount of DMF, followed by stirring at 50° C. for 30 minutes to give rise to a reaction. The reaction mixture was concentrated under vacuum to obtain 3,4-dichloroisothiazole-5-carbonyl chloride.

Provenance & Evidence