L-Isoleucine → Sodium 2-amino-3-methylpentanoate

HRID 2236133Notes

Reaction equation

HRID 2236133 reaction equation
[NH2:1][C@H:2]([C:7]([OH:9])=[O:8])[C@H:3]([CH2:5][CH3:6])[CH3:4].[OH-].[Na+:11]>O>[NH2:1][CH:2]([CH:3]([CH3:4])[CH2:5][CH3:6])[C:7]([O-:9])=[O:8].[Na+:11]

Participants

4

Reactant 2

HCID 6306L-IsoleucineHCID 14798Sodium Hydroxide

Product 1

HCID 23662724Sodium 2-amino-3-methylpentanoate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Separately, in a single-necked, round bottomed flask, equipped with a magnetic stirrer, 6.56 g (50 mmol) of Isoleucine is dissolved in 200 ml of water. To this is added 55 ml of 1M sodium hydroxide with vigorous stirring, until heat production ceases. At this point the water is removed by evaporation to yield the carboxylate salt, sodium 2-amino-3-methylpentanoate, shown below.

Workup

  1. customSeparately, in a single-necked, round bottomed flask, equipped with a magnetic stirrer
  2. temperatureuntil heat production ceases
  3. customAt this point the water is removed by evaporation

Sources & evidence

ORD record
ord-002225b4982e4fa18d9bbe29e856f901
Source dataset
uspto-grants-2010_05
Patent number
US07714154B2

Reaction notes

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