L-Leucine → HCID 23692487, compound

HRID 2236139Notes

Reaction equation

HRID 2236139 reaction equation
[NH2:1][C@H:2]([C:7]([OH:9])=[O:8])[CH2:3][CH:4]([CH3:6])[CH3:5].[OH-].[K+:11]>O>[NH2:1][CH:2]([CH2:3][CH:4]([CH3:6])[CH3:5])[C:7]([O-:9])=[O:8].[K+:11]

Participants

4

Reactant 2

HCID 6106L-LeucineHCID 14797Potassium Hydroxide

Product 1

HCID 23692487HCID 23692487, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Separately, in a single-necked, round bottomed flask, equipped with a magnetic stirrer, 7.87 g (60 mmol) of Leucine is dissolved in 300 ml of water. To this is added 72 ml of 1M potassium hydroxide with vigorous stirring, until heat production ceases. At this point the water is removed by evaporation to yield the carboxylate salt, potassium 2-amino-4-methylpentanoate, shown below.

Workup

  1. customSeparately, in a single-necked, round bottomed flask, equipped with a magnetic stirrer
  2. temperatureuntil heat production ceases
  3. customAt this point the water is removed by evaporation

Sources & evidence

ORD record
ord-4bb20ddce05a436fa55dcc4db6162224
Source dataset
uspto-grants-2010_05
Patent number
US07714154B2

Reaction notes

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