HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-nitropyrimidine → HCID 67536318, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-nitropyrimidine | HCID 82544 | — |
| Reactant | (R)-3-Pyrrolidinol | HCID 2759337 | — |
| Product | HCID 67536318 | HCID 67536318 | — |
Reaction Steps
This compound was prepared with the same method described before using (R)-3-hydroxypyrrolidine and 2-chloro-5-nitropyrimidine to give (R)—N-(5-nitro-pyrimidin-2-yl)-pyrrolidin-3-ol. LCMS calcd for C8H10N4O3 m/e 210.19, obsd 211.0 (ES, M+H). Hydrogenation of the nitro compound, as above, provided (R)—N-(5-aminopyrimidin-2-yl)-pyrrolidin-3-ol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07714126B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-2840b86d1c084a658e312c01dbb94c85 |
| Source note | uspto-grants-2010_05 |