HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-nitropyrimidine → HCID 67536697, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-nitropyrimidine | HCID 82544 | — |
| Reactant | (3S)-pyrrolidin-3-ol | HCID 2733874 | — |
| Product | HCID 67536697 | HCID 67536697 | — |
Reaction Steps
This compound was prepared with the same method described before using (S)-3-hydroxypyrrolidine and 2-chloro-5-nitro-pyrimidine to give (S)—N-(5-nitropyrimidin-2-yl)-pyrrolidin-3-ol. LCMS calcd for C8H10N4O3 m/e 210.19, obsd 211 (ES, M+H). Hydrogenation of the nitro compound, as above, provided (S)—N-(5-aminopyrimidin-2-yl)-pyrrolidin-3-ol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07714126B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-500c381b845346739c0fb8d00d555915 |
| Source note | uspto-grants-2010_05 |