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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2236215Generated: November 3, 2026

2-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acid → Dgat1-IN-3

https://huagongshe.com/reaction/2236215

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acidHCID 2776438—
ReactantN2-(2-methoxyethyl)-N2-methylpyridine-2,5-diamineHCID 52937159—
ProductDgat1-IN-3HCID 16757107—

Reaction Steps

With a procedure similar to example 1 above, 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid {6-[(2-methoxy-ethyl)-methyl-amino]-pyridin-3-yl}-amide was prepared from 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid and N2-(2-methoxy-ethyl)-N2-methyl-pyridine-2,5-diamine. LCMS calcd for C20H19F3N4O3 (m/e) 420, obsd 421 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07714126B2
Source datasetuspto-grants-2010_05
ORD IDord-ca916bed22494c5c83b95af3744a322b
Source noteuspto-grants-2010_05