Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2236216Generated: October 30, 2026

2-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acid → 2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Acid{2-[(2-Methoxyethyl)methylamino]pyrimidin-5-yl}amide

https://huagongshe.com/reaction/2236216

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acidHCID 2776438—
ReactantHCID 52937161HCID 52937161—
Product2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Acid{2-[(2-Methoxyethyl)methylamino]pyrimidin-5-yl}amideHCID 16757108—

Reaction Steps

With a procedure similar to example 1 above, 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid {2-[(2-methoxy-ethyl)-methyl-amino]-pyrimidin-5-yl}-amide was prepared from 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid and N-(2-methoxy-ethyl)-N-methyl-pyrimidine-2,5-diamine. LCMS calcd for C19H18F3N5O3 (m/e) 421, obsd 422 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07714126B2
Source datasetuspto-grants-2010_05
ORD IDord-8f04e1402dff437598bf466cc9f09a92
Source noteuspto-grants-2010_05