HCID 432067, compound → HCID 59301300, compound

HRID 2236219Notes

Reaction equation

HRID 2236219 reaction equation
[C:1]1([C:7]2[O:8][C:9]([C:15]([F:18])([F:17])[F:16])=[C:10]([C:12]([OH:14])=O)[N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[N:19]1([C:25]2[N:30]=[CH:29][C:28]([NH2:31])=[CH:27][CH:26]=2)[CH2:24][CH2:23][S:22][CH2:21][CH2:20]1>>[N:19]1([C:25]2[N:30]=[CH:29][C:28]([NH:31][C:12]([C:10]3[N:11]=[C:7]([C:1]4[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=4)[O:8][C:9]=3[C:15]([F:18])([F:17])[F:16])=[O:14])=[CH:27][CH:26]=2)[CH2:24][CH2:23][S:22][CH2:21][CH2:20]1

Participants

3

Reactant 2

HCID 432067HCID 432067, compoundHCID 27764382-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acid

Product 1

HCID 59301300HCID 59301300, compound

Procedure

With a procedure similar to example 1 above, 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid (6-thiomorpholin-4-yl-pyridin-3-yl)-amide was prepared from 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid and 6-thiomorpholin-4-yl-pyridin-3-ylamine. LCMS calcd for C20H17F3N4O2S (m/e) 434, obsd 435 (M+H).

Sources & evidence

ORD record
ord-c3df62f7a27244bd830a75162f67ce3c
Source dataset
uspto-grants-2010_05
Patent number
US07714126B2

Reaction notes

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