6-(Morpholino)pyridin-3-amine → 5-Ethyl-2-phenyl-oxazole-4-carboxylic acid (6-morpholin-4-yl-pyridin-3-yl)-amide

HRID 2236226Notes

Reaction equation

HRID 2236226 reaction equation
[CH2:1]([C:3]1[O:7][C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[N:5][C:4]=1[C:14]([OH:16])=O)[CH3:2].[N:17]1([C:23]2[N:28]=[CH:27][C:26]([NH2:29])=[CH:25][CH:24]=2)[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1>>[N:17]1([C:23]2[N:28]=[CH:27][C:26]([NH:29][C:14]([C:4]3[N:5]=[C:6]([C:8]4[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=4)[O:7][C:3]=3[CH2:1][CH3:2])=[O:16])=[CH:25][CH:24]=2)[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1

Participants

3

Reactant 2

HCID 1040596-(Morpholino)pyridin-3-amineHCID 150939472-Phenyl-5-ethyl-oxazole-4-carboxylic acid

Product 1

HCID 574019615-Ethyl-2-phenyl-oxazole-4-carboxylic acid (6-morpholin-4-yl-pyridin-3-yl)-amide

Procedure

With a procedure similar to example 16 above, 5-ethyl-2-phenyl-oxazole-4-carboxylic acid (6-morpholin-4-yl-pyridin-3-yl)-amide was prepared from 5-ethyl-2-phenyl-oxazole-4-carboxylic acid and 6-morpholin-4-yl-pyridin-3-ylamine. LCMS calcd for C21H22N4O3 (m/e) 378, obsd 379 (M+H).

Sources & evidence

ORD record
ord-d4062cb3aa0d495f9a456b7f96bb0543
Source dataset
uspto-grants-2010_05
Patent number
US07714126B2

Reaction notes

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