HCID 812168, compound → HCID 59301339, compound

HRID 2236254Notes

Reaction equation

HRID 2236254 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:10]=[C:11]([C:15]([OH:17])=O)[N:12]([CH3:14])[N:13]=2)=[CH:5][CH:4]=1.[CH3:18][O:19][CH2:20][CH2:21][N:22]([CH3:30])[C:23]1[CH:28]=[CH:27][C:26]([NH2:29])=[CH:25][N:24]=1>>[CH3:18][O:19][CH2:20][CH2:21][N:22]([CH3:30])[C:23]1[N:24]=[CH:25][C:26]([NH:29][C:15]([C:11]2[N:12]([CH3:14])[N:13]=[C:9]([C:6]3[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=3)[CH:10]=2)=[O:17])=[CH:27][CH:28]=1

Participants

3

Reactant 2

HCID 812168HCID 812168, compoundHCID 52937159N2-(2-methoxyethyl)-N2-methylpyridine-2,5-diamine

Product 1

HCID 59301339HCID 59301339, compound

Procedure

With a procedure similar to example 16 above, 5-(4-methoxy-phenyl)-2-methyl-2H-pyrazole-3-carboxylic acid {6-[(2-methoxy-ethyl)-methyl-amino]-pyridin-3-yl}-amide was prepared from 5-(4-methoxy-phenyl)-2-methyl-2H-pyrazole-3-carboxylic acid (made by hydrolysis of the corresponding commercially available ethyl ester) and N2-(2-methoxy-ethyl)-N2-methyl-pyridine-2,5-diamine. LCMS calcd for C21H25N5O3 (m/e) 395, obsd 396 (M+H). The NMR spectrum obtained on the sample is compatible with its structure.

Workup

  1. customThe NMR spectrum obtained on the sample

Sources & evidence

ORD record
ord-59c6dc26cd0b4b2eabcbb59c8b80dcf6
Source dataset
uspto-grants-2010_05
Patent number
US07714126B2

Reaction notes

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