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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2236268Generated: October 30, 2026

N2-(2-methoxyethyl)-N2-methylpyridine-2,5-diamine → 2-(2-Methoxy-phenyl)-5-trifluoromethyl-oxazole-4-carboxylic acid {6-[(2-methoxy-ethyl)-methyl-amino]-pyridin-3-yl)-amide

https://huagongshe.com/reaction/2236268

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN2-(2-methoxyethyl)-N2-methylpyridine-2,5-diamineHCID 52937159—
Reactant2-(2-Methoxy-phenyl)-5-trifluoromethyl-oxazole-4-carboxylic acidHCID 59301382—
Product2-(2-Methoxy-phenyl)-5-trifluoromethyl-oxazole-4-carboxylic acid {6-[(2-methoxy-ethyl)-methyl-amino]-pyridin-3-yl)-amideHCID 59301294—

Reaction Steps

With a procedure similar to example 16 above, 2-(2-methoxy-phenyl)-5-trifluoromethyl-oxazole-4-carboxylic acid {6-[(2-methoxy-ethyl)-methyl-amino]-pyridin-3-yl}-amide was prepared from 2-(2-methoxy-phenyl)-5-trifluoromethyl-oxazole-4-carboxylic acid and N2-(2-methoxy-ethyl)-N2-methyl-pyridine-2,5-diamine. LCMS calcd for C21H21F3N4O4 (m/e) 504. obsd 505 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07714126B2
Source datasetuspto-grants-2010_05
ORD IDord-2f8341b5a9c547aabfc281263d497d9f
Source noteuspto-grants-2010_05