HCID 20370908, compound → HCID 59301349, compound

HRID 2236270Notes

Reaction equation

HRID 2236270 reaction equation
[C:1]1([C:7]2[O:8][C:9]([CH2:15][CH2:16][CH3:17])=[C:10]([C:12]([OH:14])=O)[N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:18][O:19][CH2:20][CH2:21][N:22]([CH3:30])[C:23]1[CH:28]=[CH:27][C:26]([NH2:29])=[CH:25][N:24]=1>>[CH3:18][O:19][CH2:20][CH2:21][N:22]([CH3:30])[C:23]1[N:24]=[CH:25][C:26]([NH:29][C:12]([C:10]2[N:11]=[C:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)[O:8][C:9]=2[CH2:15][CH2:16][CH3:17])=[O:14])=[CH:27][CH:28]=1

Participants

3

Reactant 2

HCID 20370908HCID 20370908, compoundHCID 52937159N2-(2-methoxyethyl)-N2-methylpyridine-2,5-diamine

Product 1

HCID 59301349HCID 59301349, compound

Procedure

With a procedure similar to example 16 above, 2-phenyl-5-propyl-oxazole-4-carboxylic acid {6-[(2-methoxy-ethyl)-methyl-amino]-pyridin-3-yl}-amide was prepared from 2-phenyl-5-propyl-oxazole-4-carboxylic acid and N2-(2-methoxy-ethyl)-N2-methyl-pyridine-2,5-diamine. LCMS calcd for C22H26N4O3 (m/e) 394, obsd 395 (M+H).

Sources & evidence

ORD record
ord-e2f3911e96a24c3d9f2dc834bd8e100e
Source dataset
uspto-grants-2010_05
Patent number
US07714126B2

Reaction notes

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