6-(Morpholino)pyridin-3-amine → HCID 59301377, compound

HRID 2236271Notes

Reaction equation

HRID 2236271 reaction equation
[C:1]1([C:7]2[O:8][C:9]([CH2:15][CH2:16][CH3:17])=[C:10]([C:12]([OH:14])=O)[N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[N:18]1([C:24]2[N:29]=[CH:28][C:27]([NH2:30])=[CH:26][CH:25]=2)[CH2:23][CH2:22][O:21][CH2:20][CH2:19]1>>[N:18]1([C:24]2[N:29]=[CH:28][C:27]([NH:30][C:12]([C:10]3[N:11]=[C:7]([C:1]4[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=4)[O:8][C:9]=3[CH2:15][CH2:16][CH3:17])=[O:14])=[CH:26][CH:25]=2)[CH2:23][CH2:22][O:21][CH2:20][CH2:19]1

Participants

3

Reactant 2

HCID 1040596-(Morpholino)pyridin-3-amineHCID 20370908HCID 20370908, compound

Product 1

HCID 59301377HCID 59301377, compound

Procedure

With a procedure similar to example 16 above, 2-phenyl-5-propyl-oxazole-4-carboxylic acid (6-morpholin-4-yl-pyridin-3-yl)-amide was prepared from 2-phenyl-5-propyl-oxazole-4-carboxylic acid and 6-morpholin-4-yl-pyridin-3-ylamine. LCMS calcd for C22H24N4O3 (m/e) 392, obsd 393 (M+H).

Sources & evidence

ORD record
ord-75def691f8d64682a5f835b4eef7ff79
Source dataset
uspto-grants-2010_05
Patent number
US07714126B2

Reaction notes

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