HCID 43263136, compound → HCID 59301390, compound

HRID 2236274Notes

Reaction equation

HRID 2236274 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[O:9][C:10]([CH2:16][CH2:17][CH3:18])=[C:11]([C:13]([OH:15])=O)[N:12]=1.[CH2:19]([N:21]([CH3:29])[C:22]1[CH:27]=[CH:26][C:25]([NH2:28])=[CH:24][N:23]=1)[CH3:20]>>[CH2:19]([N:21]([CH3:29])[C:22]1[N:23]=[CH:24][C:25]([NH:28][C:13]([C:11]2[N:12]=[C:8]([C:3]3[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=3[Cl:1])[O:9][C:10]=2[CH2:16][CH2:17][CH3:18])=[O:15])=[CH:26][CH:27]=1)[CH3:20]

Participants

3

Reactant 2

HCID 43263136HCID 43263136, compoundHCID 59301441HCID 59301441, compound

Product 1

HCID 59301390HCID 59301390, compound

Procedure

With a procedure similar to example 16 above, 2-(2-chloro-phenyl)-5-propyl-oxazole-4-carboxylic acid [6-(ethyl-methyl-amino)-pyridin-3-yl]-amide was prepared from 2-(2-chloro-phenyl)-5-propyl-oxazole-4-carboxylic acid and N2-ethyl-N2-methyl-pyridine-2,5-diamine. LCMS calcd for C21H23ClN4O2 (m/e) 398, obsd 399 (M+H).

Sources & evidence

ORD record
ord-aeb6e2f91b7f45be9dfafb06028af5ed
Source dataset
uspto-grants-2010_05
Patent number
US07714126B2

Reaction notes

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