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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2236277Generated: November 1, 2026

2-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acid → HCID 57393260, compound

https://huagongshe.com/reaction/2236277

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acidHCID 2776438—
Reactant2-((5-Aminopyridin-2-yl)(methyl)amino)ethanolHCID 22693630—
ProductHCID 57393260HCID 57393260—

Reaction Steps

With a procedure similar to example 43 above, 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid {6-[(2-hydroxy-ethyl)-methyl-amino]-pyridin-3-yl}-amide was prepared from 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid and 2-[(5-amino-pyridin-2-yl)-methyl-amino]-ethanol. LCMS calcd for C19H17F3N4O3 (m/e) 406, obsd 407 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07714126B2
Source datasetuspto-grants-2010_05
ORD IDord-a0f8bf90abcf4153840260482a289e1c
Source noteuspto-grants-2010_05