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HRID2236278

反应详情

EQUATION

反应方程式

HRID 2236278 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1nc(-c2ccccc2)oc1C(F)(F)F
HCID2776438

2-Phenyl-5-(trifluoromethyl)oxazole-4-carboxylic acid

C11H6F3NO3

结构：Nc1ccc(N2CCC(O)C2)nc1
HCID53408167

1-(5-Aminopyridin-2-yl)pyrrolidin-3-ol

C9H13N3O

PRODUCTS

生成物

1
结构：O=C(Nc1ccc(N2CCC(O)C2)nc1)c1nc(-c2ccccc2)oc1C(F)(F)F
HCID59301346

未命名化合物

PROCEDURE

实验过程

With a procedure similar to example 43 above, 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid [6-(3-hydroxy-pyrrolidin-1-yl)-pyridin-3-yl]-amide was prepared from 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid and 1-(5-amino-pyridin-2-yl)-pyrrolidin-3-ol. LCMS calcd for C20H17F3N4O3 (m/e) 418, obsd 419 (M+H).