Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2236280Generated: October 30, 2026

2-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acid → HCID 59301453, compound

https://huagongshe.com/reaction/2236280

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acidHCID 2776438—
ReactantHCID 59301329HCID 59301329—
ProductHCID 59301453HCID 59301453—

Reaction Steps

With a method similar to example 43 above, (R)-2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid-[2-(3-hydroxypyrrolidin-1-yl)pyrimidin-5-yl]amide was prepared from 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid and (R)—N-(5-aminopyrimidin-2-yl)-pyrrolidin-3-ol. LCMS calcd for C19H16F3N5O3 m/e 419.37, obsd 420.1 (ES, M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07714126B2
Source datasetuspto-grants-2010_05
ORD IDord-4ba4dac845674fd6967f1c42cb1135d9
Source noteuspto-grants-2010_05