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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2236283Generated: October 31, 2026

2-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acid → HCID 59301333, compound

https://huagongshe.com/reaction/2236283

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acidHCID 2776438—
ReactantHCID 59301421HCID 59301421—
ProductHCID 59301333HCID 59301333—

Reaction Steps

With a procedure similar to example 43 above, 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid [6-((S)-2-hydroxymethyl-pyrrolidin-1-yl)-pyridin-3-yl]-amide was prepared from 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid and [(S)-1-(5-amino-pyridin-2-yl)-pyrrolidin-2-yl]-methanol. LCMS calcd for C21H19F3N4O3 (m/e) 432, obsd 433 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07714126B2
Source datasetuspto-grants-2010_05
ORD IDord-542a9427db4e462da8fc0478e5cca521
Source noteuspto-grants-2010_05