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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2236284Generated: October 31, 2026

2-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acid → HCID 59301384, compound

https://huagongshe.com/reaction/2236284

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acidHCID 2776438—
Reactant1-(5-Aminopyridin-2-yl)piperidin-4-olHCID 16781994—
ProductHCID 59301384HCID 59301384—

Reaction Steps

With a procedure similar to example 43 above, 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid (4-hydroxy-3,4,5,6-tetrahydro-2H-[1,2′]bipyridinyl-5′-yl)-amide was prepared from 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid and 5′-amino-3,4,5,6-tetrahydro-2H-[1,2′]bipyridinyl-4-ol. LCMS calcd for C21H19F3N4O3 (m/e) 432, obsd 433 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07714126B2
Source datasetuspto-grants-2010_05
ORD IDord-59cc45fecb314f49a2c172a9b8366713
Source noteuspto-grants-2010_05