6-(Morpholino)pyridin-3-amine → HCID 59301308, compound

HRID 2236291Notes

Reaction equation

HRID 2236291 reaction equation
O=C1CCC(=O)N1O[C:9]([C:11]1[O:15][C:14]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=2[CH3:22])=[N:13][C:12]=1[CH3:23])=[O:10].[N:24]1([C:30]2[N:35]=[CH:34][C:33]([NH2:36])=[CH:32][CH:31]=2)[CH2:29][CH2:28][O:27][CH2:26][CH2:25]1>>[N:24]1([C:30]2[N:35]=[CH:34][C:33]([NH:36][C:9]([C:11]3[O:15][C:14]([C:16]4[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=4[CH3:22])=[N:13][C:12]=3[CH3:23])=[O:10])=[CH:32][CH:31]=2)[CH2:29][CH2:28][O:27][CH2:26][CH2:25]1

Participants

3

Reactant 2

HCID 1040596-(Morpholino)pyridin-3-amineHCID 59301344HCID 59301344, compound

Product 1

HCID 59301308HCID 59301308, compound

Procedure

With a procedure similar to example 50 above, 4-methyl-2-o-tolyl-oxazole-5-carboxylic acid (6-morpholin-4-yl-pyridin-3-yl)-amide was prepared from 4-methyl-2-o-tolyl-oxazole-5-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester and 6-morpholin-4-yl-pyridin-3-ylamine. LCMS calcd for C21H22N4O3 (m/e) 378, obsd 379 (M+H).

Sources & evidence

ORD record
ord-79961576cc39409c98b5944a346f2b94
Source dataset
uspto-grants-2010_05
Patent number
US07714126B2

Reaction notes

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