6-(Morpholino)pyridin-3-amine → HCID 57401962, compound

HRID 2236293Notes

Reaction equation

HRID 2236293 reaction equation
O=C1CCC(=O)N1O[C:9]([C:11]1[O:15][C:14]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[N:13][C:12]=1[CH3:22])=[O:10].[N:23]1([C:29]2[N:34]=[CH:33][C:32]([NH2:35])=[CH:31][CH:30]=2)[CH2:28][CH2:27][O:26][CH2:25][CH2:24]1>>[N:23]1([C:29]2[N:34]=[CH:33][C:32]([NH:35][C:9]([C:11]3[O:15][C:14]([C:16]4[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=4)=[N:13][C:12]=3[CH3:22])=[O:10])=[CH:31][CH:30]=2)[CH2:28][CH2:27][O:26][CH2:25][CH2:24]1

Participants

3

Reactant 2

HCID 1040596-(Morpholino)pyridin-3-amineHCID 59301395HCID 59301395, compound

Product 1

HCID 57401962HCID 57401962, compound

Procedure

With a procedure similar to example 50 above, 4-methyl-2-phenyl-oxazole-5-carboxylic acid (6-morpholin-4-yl-pyridin-3-yl)-amide was prepared from 4-methyl-2-phenyl-oxazole-5-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester and 6-morpholin-4-yl-pyridin-3-ylamine. LCMS calcd for C20H20N4O3 (m/e) 364, obsd 365 (M+H).

Sources & evidence

ORD record
ord-78dd9ab7c16b4551b351cd70df25fa0e
Source dataset
uspto-grants-2010_05
Patent number
US07714126B2

Reaction notes

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