HuagongsheHuagongshe Chemistry Print Report · For research reference only
N2-(2-methoxyethyl)-N2-methylpyridine-2,5-diamine → 2-(2-Chloro-phenyl)-4-ethyl-oxazole-5-carboxylic acid {6-[(2-methoxy-ethyl)-methyl-amino]-pyridin-3-yl}-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N2-(2-methoxyethyl)-N2-methylpyridine-2,5-diamine | HCID 52937159 | — |
| Reactant | 2-(2-Chloro-phenyl)-4-ethyl-oxazole-5-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester | HCID 59301312 | — |
| Product | 2-(2-Chloro-phenyl)-4-ethyl-oxazole-5-carboxylic acid {6-[(2-methoxy-ethyl)-methyl-amino]-pyridin-3-yl}-amide | HCID 59301391 | — |
Reaction Steps
With a procedure similar to example 50 above, 2-(2-chloro-phenyl)-4-ethyl-oxazole-5-carboxylic acid {6-[(2-methoxy-ethyl)-methyl-amino]-pyridin-3-yl}-amide was prepared from 2-(2-chloro-phenyl)-4-ethyl-oxazole-5-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester and N2-(2-methoxy-ethyl)-N2-methyl-pyridine-2,5-diamine. LCMS calcd for C21H23ClN4O3 (m/e) 414, obsd 415 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07714126B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-8bc2bebb5ae3406fb001613ee700a072 |
| Source note | uspto-grants-2010_05 |