6-(Morpholino)pyridin-3-amine → HCID 59301447, compound

HRID 2236299Notes

Reaction equation

HRID 2236299 reaction equation
O=C1CCC(=O)N1O[C:9]([C:11]1[O:15][C:14]([CH:16]2[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]2)=[N:13][C:12]=1[CH2:22][CH2:23][CH3:24])=[O:10].[N:25]1([C:31]2[N:36]=[CH:35][C:34]([NH2:37])=[CH:33][CH:32]=2)[CH2:30][CH2:29][O:28][CH2:27][CH2:26]1>>[N:25]1([C:31]2[N:36]=[CH:35][C:34]([NH:37][C:9]([C:11]3[O:15][C:14]([CH:16]4[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21]4)=[N:13][C:12]=3[CH2:22][CH2:23][CH3:24])=[O:10])=[CH:33][CH:32]=2)[CH2:30][CH2:29][O:28][CH2:27][CH2:26]1

Participants

3

Reactant 2

HCID 1040596-(Morpholino)pyridin-3-amineHCID 59301418HCID 59301418, compound

Product 1

HCID 59301447HCID 59301447, compound

Procedure

With a procedure similar to example 50 above, 2-cyclohexyl-4-propyl-oxazole-5-carboxylic acid (6-morpholin-4-yl-pyridin-3-yl)-amide was prepared from 2-cyclohexyl-4-propyl-oxazole-5-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester and 6-morpholin-4-yl-pyridin-3-ylamine. LCMS calcd for C22H30N4O3 (m/e) 398, obsd 399 (M+H).

Sources & evidence

ORD record
ord-4da8d42b1ad24ff480348ea626eb8e0d
Source dataset
uspto-grants-2010_05
Patent number
US07714126B2

Reaction notes

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