反应详情

With a procedure similar to example 50 above, 2-(2-chloro-phenyl)-4-propyl-oxazole-5-carboxylic acid [6-(cyclopropyl-methyl-amino)-pyridin-3-yl]-amide was prepared from 2-(2-chloro-phenyl)-4-propyl-oxazole-5-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester and N2-cyclopropyl-N2-methyl-pyridine-2,5-diamine. LCMS calcd for C22H23ClN4O2 (m/e) 410, obsd 411 (M+H).