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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2236305Generated: November 1, 2026

N2-(2-methoxyethyl)-N2-methylpyridine-2,5-diamine → N-(6-((2-Methoxyethyl)(methyl)amino)pyridin-3-yl)-2-phenyl-4-(trifluoromethyl)oxazole-5-carboxamide

https://huagongshe.com/reaction/2236305

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN2-(2-methoxyethyl)-N2-methylpyridine-2,5-diamineHCID 52937159—
Reactant2-Phenyl-4-(trifluoromethyl)oxazole-5-carboxylic acidHCID 59301443—
ProductN-(6-((2-Methoxyethyl)(methyl)amino)pyridin-3-yl)-2-phenyl-4-(trifluoromethyl)oxazole-5-carboxamideHCID 16112851—

Reaction Steps

With a procedure similar to example 1 above, 2-phenyl-4-trifluoromethyl-oxazole-5-carboxylic acid {6-[(2-methoxy-ethyl)-methyl-amino]-pyridin-3-yl}-amide was prepared from 2-phenyl-4-trifluoromethyl-oxazole-5-carboxylic acid and N2-(2-methoxy-ethyl)-N2-methyl-pyridine-2,5-diamine. LCMS calcd for C20H19F3N4O3 (m/e) 420, obsd 421 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07714126B2
Source datasetuspto-grants-2010_05
ORD IDord-fd25a9eb91ac4e2082d18318a013beb3
Source noteuspto-grants-2010_05