N2-(2-methoxyethyl)-N2-methylpyridine-2,5-diamine → HCID 59301455, compound

HRID 2236309Notes

Reaction equation

HRID 2236309 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12]1[O:13][C:14]([C:21](O)=[O:22])=[C:15]([C:17]([F:20])([F:19])[F:18])[N:16]=1.[CH3:24][O:25][CH2:26][CH2:27][N:28]([CH3:36])[C:29]1[CH:34]=[CH:33][C:32]([NH2:35])=[CH:31][N:30]=1>>[CH3:24][O:25][CH2:26][CH2:27][N:28]([CH3:36])[C:29]1[N:30]=[CH:31][C:32]([NH:35][C:21]([C:14]2[O:13][C:12]([C:7]3[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=3[O:5][CH2:4][CH2:3][O:2][CH3:1])=[N:16][C:15]=2[C:17]([F:18])([F:19])[F:20])=[O:22])=[CH:33][CH:34]=1

Participants

3

Reactant 2

HCID 52937159N2-(2-methoxyethyl)-N2-methylpyridine-2,5-diamineHCID 59301436HCID 59301436, compound

Product 1

HCID 59301455HCID 59301455, compound

Procedure

With a procedure similar to example 1 above, 2-[2-(2-methoxy-ethoxy)-phenyl]-4-trifluoromethyl-oxazole-5-carboxylic acid {6-[(2-methoxy-ethyl)-methyl-amino]-pyridin-3-yl}-amide was prepared from 2-[2-(2-methoxy-ethoxy)-phenyl]-4-trifluoromethyl-oxazole-5-carboxylic acid and N2-(2-methoxy-ethyl)-N2-methyl-pyridine-2,5-diamine. LCMS calcd for C23H25F3N4O5 (m/e) 494, obsd 495 (M+H).

Sources & evidence

ORD record
ord-84cec0995071434d8ed078d6b64d9aa8
Source dataset
uspto-grants-2010_05
Patent number
US07714126B2

Reaction notes

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