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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2236357Generated: October 25, 2026

3-Butyn-2-amine, 2-methyl- → N-(1,1-dimethyl-2-propynyl)-3,5-difluoro-4-(2-propynyloxy)benzamide

https://huagongshe.com/reaction/2236357

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Butyn-2-amine, 2-methyl-HCID 76319—
Reactant3,5-Difluoro-4-(2-propynyloxy)benzoyl chlorideHCID 57445696—
ProductN-(1,1-dimethyl-2-propynyl)-3,5-difluoro-4-(2-propynyloxy)benzamideHCID 59301819—

Reaction Steps

According to the same method as that of Production Example 1, 1,1-dimethyl-2-propynylamine was used in place of 2,2-dimethylpropylamine, 3,5-difluoro-4-(2-propynyloxy)benzoyl chloride was used in place of 4-(2-propynyloxy)-3-methoxybenzoyl chloride to obtain N-(1,1-dimethyl-2-propynyl)-3,5-difluoro-4-(2-propynyloxy)benzamide (hereinafter, described as the compound 51 of the present invention) represented by the formula:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07714168B2
Source datasetuspto-grants-2010_05
ORD IDord-71b8171656b943cfb46409cd287a8b7a
Source noteuspto-grants-2010_05