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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2236358Generated: October 25, 2026

3-Ethylpent-1-yn-3-amine → N-(1,1-diethyl-2-propynyl)-3,5-difluoro-4-(2-propynyloxy)benzamide

https://huagongshe.com/reaction/2236358

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Ethylpent-1-yn-3-amineHCID 76710—
Reactant3,5-Difluoro-4-(2-propynyloxy)benzoyl chlorideHCID 57445696—
ProductN-(1,1-diethyl-2-propynyl)-3,5-difluoro-4-(2-propynyloxy)benzamideHCID 59301827—

Reaction Steps

According to the same method as that of Production Example 1, 1,1-diethyl-2-propynylamine was used in place of 2,2-dimethylpropylamine, 3,5-difluoro-4-(2-propynyloxy)benzoyl chloride was used in place of 4-(2-propynyloxy)-3-methoxybenzoyl chloride to obtain N-(1,1-diethyl-2-propynyl)-3,5-difluoro-4-(2-propynyloxy)benzamide (hereinafter, described as the compound 52 of the present invention) represented by the formula:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07714168B2
Source datasetuspto-grants-2010_05
ORD IDord-ed91547e90744c1289436e74d2df417a
Source noteuspto-grants-2010_05