2-Amino-2,3-dimethylbutyronitrile → HCID 59301805, compound

HRID 2236359Notes

Reaction equation

HRID 2236359 reaction equation
[CH3:1][C:2]([NH2:8])([C:6]#[N:7])[CH:3]([CH3:5])[CH3:4].[F:9][C:10]1[CH:11]=[C:12]([CH:16]=[C:17]([F:23])[C:18]=1[O:19][CH2:20][C:21]#[CH:22])[C:13](Cl)=[O:14]>>[CH3:1][C:2]([NH:8][C:13](=[O:14])[C:12]1[CH:16]=[C:17]([F:23])[C:18]([O:19][CH2:20][C:21]#[CH:22])=[C:10]([F:9])[CH:11]=1)([C:6]#[N:7])[CH:3]([CH3:5])[CH3:4]

Participants

3

Reactant 2

HCID 943552-Amino-2,3-dimethylbutyronitrileHCID 574456963,5-Difluoro-4-(2-propynyloxy)benzoyl chloride

Product 1

HCID 59301805HCID 59301805, compound

Procedure

According to the same method as that of Production Example 1, 1,2-dimethyl-1-cyanopropylamine was used in place of 2,2-dimethylpropylamine, 3,5-difluoro-4-(2-propynyloxy)benzoyl chloride was used in place of 4-(2-propynyloxy)-3-methoxybenzoyl chloride to obtain N-(1,2-dimethyl-1-cyanopropyl)-3,5-difluoro-4-(2-propynyloxy)benzamide (hereinafter, described as the compound 53 of the present invention) represented by the formula:

Sources & evidence

ORD record
ord-c5fcc4852fc747a8b7f347bee9a54bce
Source dataset
uspto-grants-2010_05
Patent number
US07714168B2

Reaction notes

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