6-Hydroxymethylindole → 1H-Indole-6-carboxaldehyde

Participants

Reaction Steps

To a dissolved solution of (1H-Indol-6-yl)-methanol (100 mg, 0.68 mmole) in dichloromethane (31 ml), manganese (IV) oxide (1.9 g, 21.9 mmol) is added. The reaction mixture stirred at room temperature for 8 hours and then passed through celite. The reaction mixture is then concentrated to give a yellow oil (80 mg, 0.55 mmole). MS (ESI) m/z 146.2 (M+1).

Provenance & Evidence