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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2236433Generated: October 31, 2026

1H-indol-4-ylmethanol → Indole-4-carboxaldehyde

https://huagongshe.com/reaction/2236433

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-indol-4-ylmethanolHCID 2773457—
CatalystHCID 178418406HCID 178418406—
SolventDichloromethaneHCID 6344—
ProductIndole-4-carboxaldehydeHCID 33370389.9%

Reaction Steps

To a dissolved solution of (1H-Indol-4-yl)-methanol (100 mg, 0.69 mmole) in dichloromethane (0.500 ml), manganese (IV) oxide (597 mg, 6.9 mmol) is added. The reaction mixture stirred at room temperature for 8 hours and then passed through Celite. The reaction mixture is then concentrated to give a yellow oil (90 mg). MS (ESI) m/z 146.1 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07713994B2
Source datasetuspto-grants-2010_05
ORD IDord-bec4b63fe9b145b1abe04cc47ee81ac2
Source noteuspto-grants-2010_05