4-Chloromethyl-2-methoxy-biphenyl → 1-Butyl-4-chloromethyl-2-methoxy-benzene

HRID 2236464Notes

Reaction equation

HRID 2236464 reaction equation
[Cl:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2C=C[CH:12]=[CH:11][CH:10]=2)=[C:5]([O:15][CH3:16])[CH:4]=1.C(C1C=CC(CO)=CC=1OC)CCC>>[CH2:9]([C:6]1[CH:7]=[CH:8][C:3]([CH2:2][Cl:1])=[CH:4][C:5]=1[O:15][CH3:16])[CH2:10][CH2:11][CH3:12]

Participants

3

Reactant 2

HCID 593001244-Chloromethyl-2-methoxy-biphenylHCID 59300341(4-Butyl-3-methoxy-phenyl)-methanol

Product 1

HCID 593002161-Butyl-4-chloromethyl-2-methoxy-benzene

Procedure

Following the same procedure for the preparation of 4-Chloromethyl-2-methoxy-biphenyl, the title compound is prepared from (4-Butyl-3-methoxy-phenyl)-methanol (crude material from the previous step). The crude material is used directly in the next step.

Sources & evidence

ORD record
ord-39c36ffb60c044b4abf34ee7d106765f
Source dataset
uspto-grants-2010_05
Patent number
US07713994B2

Reaction notes

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