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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2236468Generated: October 31, 2026

4-Chloromethyl-2-methoxy-biphenyl → 4-Chloromethyl-4'-fluoro-2-methoxy-biphenyl

https://huagongshe.com/reaction/2236468

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloromethyl-2-methoxy-biphenylHCID 59300124—
Reactant(4'-Fluoro-2-methoxy-biphenyl-4-yl)-methanolHCID 59300176—
Product4-Chloromethyl-4'-fluoro-2-methoxy-biphenylHCID 59300183—

Reaction Steps

Following the same procedure for the preparation of 4-Chloromethyl-2-methoxy-biphenyl, the title compound is prepared from (4′-Fluoro-2-methoxy-biphenyl-4-yl)-methanol (crude material from the previous step). The crude material is used directly in the next step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07713994B2
Source datasetuspto-grants-2010_05
ORD IDord-aaa9e36d84f14fa7b7d01fd351cf8d48
Source noteuspto-grants-2010_05