Cesium carbonate → HCID 59299836, compound

Participants

Reaction Conditions

Reaction Steps

4-Bromo-2-fluoro-5-methoxymethoxy-benzaldehyde (160 mg, 0.61 mmol) and 3-furanboronic acid (100 mg, 0.90 mmol) and Pd(PPh3)4 (60 mg, 0.052 mmol) and Cs2CO3 (400 mg, 1.23 mmol) were mixed in N,N-dimethylformamide (10 mL) and degassed and then heated at 100° C. for 1 hour. The mixture is allowed to cool to room temperature and an aqueous work up is performed. The residue is purified to afford the desired product (60 mg, 39%).

Provenance & Evidence