HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 2-(4-aminophenyl)pyrrolidine-1-carboxylate → 4-(2-Ethyl-pyrrolidin-1-ylmethyl)-phenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 2-(4-aminophenyl)pyrrolidine-1-carboxylate | HCID 44607625 | — |
| Reactant | 1-(4-Nitro-benzyl)-2-vinyl-pyrrolidine | HCID 59300171 | — |
| Product | 4-(2-Ethyl-pyrrolidin-1-ylmethyl)-phenylamine | HCID 59299936 | 44% |
Reaction Steps
Using the same procedure described for the preparation of 2-(4-Amino-phenyl)-pyrrolidine-1-carboxylic acid tert-butyl ester, the title compound is prepared from 1-(4-Nitro-benzyl)-2-vinyl-pyrrolidine (220 mg, 0.95 mmol) in 44% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07713994B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-296ef2ad0be648b3a67c424529090f87 |
| Source note | uspto-grants-2010_05 |