HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Phenylthioethanethiol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethylene Oxide | HCID 6354 | — |
| Reactant | Thiophenol | HCID 7969 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 2-(Phenylthio)ethanol | HCID 69685 | — |
| Reactant | Thiourea | HCID 2723790 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Phenylthioethanethiol | HCID 23503969 | — |
Reaction Steps
77 g of 2-phenylthioethanol, (0.5 mol, prepared from thiophenol and ethylene oxide in the presence of some potassium hydroxide) are maintained for 4 hours under reflux with 40 g of thiourea and 50 g of 37% hydrochloric acid. At 40° C., the reaction mixture is stirred with 50 g of 50% hydrazine hydrate solution for 30 minutes. 100 ml of toluene are added, this is maintained for 30 minutes in the steam bath, the toluene phase is separated off and compressed under vacuum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04355185 |
| Source dataset | uspto-grants-1982_10 |
| ORD ID | ord-cf8da0c2aaf54b18a49b46c8662c59e6 |
| Source note | uspto-grants-1982_10 |