Sulfuric Acid → HCID 178526276, compound

HRID 223659Notes

Reaction equation

HRID 223659 reaction equation
C([O:8][N:9]1[CH2:13][CH2:12][NH:11][C:10]1=[N:14][C:15]1[C:20]([Cl:21])=[CH:19][CH:18]=[CH:17][C:16]=1[Cl:22])C1C=CC=CC=1.S(=O)(=O)(O)O.[H][H]>[Pt]=O.C(O)(=O)C>[Cl:21][C:20]1[CH:19]=[CH:18][CH:17]=[C:16]([Cl:22])[C:15]=1[N:14]=[C:10]1[NH:11][CH2:12][CH2:13][N:9]1[OH:8]

Participants

6

Reactant 3

HCID 1118Sulfuric AcidHCID 178418361HCID 178418361, compoundHCID 178478106HCID 178478106, compound

Product 1

HCID 178526276HCID 178526276, compound

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 176Acetic AcidSolvent

Procedure

8.4 g. of 1-benzyloxy-2-[(2,6-dichlorophenyl)imino]imidazolidine in 30 ml. of glacial acetic acid and 2.5 ml. of concentrated sulfuric acid are hydrogenated under normal pressure in the presence of 300 mg. of platinum oxide. After the uptake of hydrogen has ended, the catalyst is filtered off and the filtrate is evaporated. The residue is dissolved in water and the solution is rendered alkaline with sodium carbonate. The precipitate which has formed is filtered off, washed with a little water and dried in vacuo, whereupon 2-[(2,6-dichlorophenyl)imino]-1-hydroxyimidazolidine, m.p. 215°-216°, is obtained.

Workup

  1. filtrationthe catalyst is filtered off
  2. customthe filtrate is evaporated
  3. dissolutionThe residue is dissolved in water
  4. customThe precipitate which has formed
  5. filtrationis filtered off
  6. washwashed with a little water
  7. dry with materialdried in vacuo, whereupon 2-[(2,6-dichlorophenyl)imino]-1-hydroxyimidazolidine, m.p. 215°-216°
  8. customis obtained

Sources & evidence

ORD record
ord-1467cac4f6bb44f3bb98d947cba01703
Source dataset
uspto-grants-1982_10
Patent number
US04355033

Reaction notes

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