Triethylamine → HCID 178518280, compound

Participants

Reaction Steps

To a mixture of 6-bromo-4-methoxymethylene-4H-isoquinoline-1,3-dione (400 mg, 1.42 mmol) and 2-aminomethyl-benzene-1,4-diol hydrochloride salt (250 mg, 1.42 mmol) in N,N-dimethylformamide (DMF) (10 mL) is added triethylamine (Et3N) (0.3 mL, 2.13 mmol). The resulting precipitate is filtered to give 89 mg (16.1%) of the title compound as a beige solid. MS (ESI) m/z 387.0 (M−H)−1.

Provenance & Evidence