Hydrochloric Acid → HCID 68699088, compound

Participants

Reaction Steps

A solution of 6-azidomethyl-4-benzyloxy-2,2-dimethyl-benzo[1,3]dioxole (2.0 mmol maximum) in ethanol (20 mL) and 6 M aqueous hydrochloric acid (2 mL) is hydrogenated at 50 psi over 5% Pd/C. After 18 hours, the reaction mixture is filtered through a Celite pad and concentrated under reduced pressure to give C-(7-benzyloxy-2,2-dimethyl-benzo[1,3]dioxol-5-yl)-methylamine hydrochloride.

Provenance & Evidence