HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyl-4-(4-nitrophenyl)-1,4-diazepane → 4-(4-Methyl-1,4-diazepan-1-yl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyl-4-(4-nitrophenyl)-1,4-diazepane | HCID 3124722 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(4-Methyl-1,4-diazepan-1-yl)aniline | HCID 13007951 | — |
Reaction Steps
A solution 1-methyl-4-(4-nitrophenyl)-1,4-diazepane in ethanol is hydrogenated overnight at atmospheric pressure over 10% Pd/C. The mixture is filtered through a pad of diatomaceous earth and concentrated under reduced pressure to give 4-(4-methyl-[1,4]-diazepan-1-yl)phenylamine as a dark maroon oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07713994B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-e32bfe369953471bbb0f5579b3eddeae |
| Source note | uspto-grants-2010_05 |