HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl-[2-(4-nitro-benzenesulfonyl)-ethyl]-amine → 4-((2-(Dimethylamino)ethyl)sulfonyl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl-[2-(4-nitro-benzenesulfonyl)-ethyl]-amine | HCID 68698682 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-((2-(Dimethylamino)ethyl)sulfonyl)aniline | HCID 20336821 | — |
Reaction Steps
A solution of dimethyl-[2-(4-nitro-benzenesulfonyl)-ethyl]-amine (0.39 mmol) in ethanol (15 mL) is hydrogenated for 90 minutes at atmospheric pressure over 10% Pd/C. The mixture is filtered through a pad of diatomaceous earth and concentrated under reduced pressure to give 4-(2-dimethylamino-ethanesulfonyl)-phenylamine as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07713994B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-b341f782ca484939a71b61f0a8df9eb6 |
| Source note | uspto-grants-2010_05 |