HCID 178429948, compound → 4-(Morpholinomethyl)aniline

Participants

Reaction Steps

Using the procedure described for the preparation of 4Z)-6-bromo-4-({[4-(3,5-dimethylpiperazin-1-yl)phenyl]amino}methylene)isoquinoline-1,3(2H,4H)-dione (24), 2.38 g (75.9% yield) of light brown solid is obtained from 2.0 g (7.09 mmol) of (4E)-6-bromo-4-(methoxymethylene)isoquinoline-1,3(2H,4H)-dione, and 1.63 g (8.5 mmol) of 4-Morpholin-4-ylmethyl-phenylamine mp 209-210° C.; MS (ESI) m/z 442.1 (M+H)+1

Provenance & Evidence